NAVIGATOR: An Imaging Biobank to Precisely Prevent and Predict cancer, and facilitate the Participation of oncologic patients to Diagnosis and Treatment

NAVIGATOR project aims to boost 4P precision medicine in oncology by advancing translational research based on quantitative imaging and multi-omics analyses, towards a better understanding of cancer biology, cancer care, and, more generally, cancer risk. The project will deliver a technological solution relying on:

• an open imaging Biobank, collecting and preserving large amount of quality, standardised imaging data and related omics data in a secure and privacy-preserving model. Data will include CT, MRI and PET data for various tumour settings, clinical data from regional healthcare services, molecular and liquid biopsy data
• an open-science oriented Virtual Research Environment, available for medical researchers and general clinical stakeholders, to process the multi-omics data to (i) extract gold-standard and novel imaging biomarkers based on Radiomics analyses; and (ii) create and test digital patient models, through Big data analytics and Artificial Intelligence techniques, mining cancer phenotypes, stratified risks and responsivity to therapy.